Pharmaceutics Calculations Practice Set #8 with Answers


Question 1
An intravenous infusion contains 1 g of carbenicillin in each 20 mL. How many milliliters of the infusion should be administered daily to a 154-lb patient if the dose of carbenicillin is 200 mg/kg per day?
A. 0.28 mL
B. 0.5 mL
C. 280 mL
D. 500 mL

Question 2
The pediatric dose of cefadroxil is 30 mg/kg/day. If a child was given a daily dose of 2 teaspoonfuls of a pediatric suspension containing 125 mg of cefadroxil per 5 mL, what was the weight, in pounds, of the child?
A. 18.33 lbs
B. 8.33 lbs.
C. 10 lbs
D. 183.3 lbs

Question 3
If the administration of gentamicin at a dose of 1.75 mg/kg is determined to result in peak blood serum levels of 4 mcg/mL, calculate the dose, in milligrams, for a 120-lb. patient that may be expected to result in a blood serum gentamicin level of 4.5 mcg/mL.
Hint: Assume linear increase of dose upon increase of peak conc.
A. 107.4 g
B. 236.25 g
C. 107.4 mg
D. 236.25 mg

Question 4
The loading dose of indomethacin in neonates is 0.2 mg/kg of body weight by intravenous infusion. a. What would be the dose for a neonate weighing 6 lb 4 oz? b. How many milliliters of an injection containing 1 mg of indomethacin per 0.5 mL should be administered to obtain this dose?
A. a. 0.5918 mg
b. 0.294 mL
B. a. 568 mg
b. 284 mL
C. a. 0.568 mg
b. 0.284 mL
D. a. 0.548 mg
b. 0.294 mL

Question 5
The usual initial dose of chlorambucil is 150 mcg/kg of body weight. How many mg should be administered to a person weighing 154 lb?
A. 10,500 mg
B. 105 mg
C. 1.05 mg
D. 10.5 mg

Question 6
The usual dose of acetaminophen is 15 mg/kg. How may milligrams should be administered to a child weighing 44 lb? How many mL would be given if the syrup concentrations is 150 mg/5 mL?
A. 2 mL
B. 4 mL
C. 10 mL
D. 8 mL

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